Global Kratom Coalition Applauds Kentucky’s Action to Become the Second State to Schedule Concentrated Synthetic 7-OH Products

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FRANKFORT, KY, November 5, 2025 (EZ Newswire) -- The Global Kratom Coalition (GKC) today praised Kentucky Governor Andy Beshear and the Kentucky Cabinet for Health and Family Services for moving to classify concentrated or isolated, synthetic 7-hydroxymitragynine (7-OH) as a Schedule I narcotic, making it illegal to sell, possess, or distribute in the Commonwealth. The rule limits the allowable concentrations of 7-OH to 400 parts per million (0.04%) by dry weight, effectively removing concentrated synthetic 7-OH opioid products from the market while leaving natural kratom leaf unaffected. 

This decisive step follows the July 29th, 2025, actions taken by the U.S Food and Drug Administration (FDA) which recommended the scheduling of concentrated synthetic 7-OH to the Drug Enforcement Administration (DEA). Following this, on August 13th, 2025, James Uthmeier, Attorney General of Florida, issued an emergency rule that immediately classified concentrated synthetic 7‑hydroxymitragynine (7-OH) as a Schedule I controlled substance. Both the FDA and Florida’s rule explicitly distinguish natural kratom leaf from synthetic 7-OH, confirming that natural kratom leaf products are not the focus of these scheduling actions

“This is a major step forward for consumer safety,” said Matthew Lowe, Executive Director of the Global Kratom Coalition. “Governor Beshear and his administration are protecting Kentuckians from dangerous, concentrated synthetic 7-OH opioid products, while preserving access to natural kratom leaf, a botanical with safe consumption for more than 50 years in the U.S. by more than 23 million Americans. This is exactly the kind of leadership we need across the country.”

Unlike concentrated synthetic 7-OH opioid products, natural kratom leaf contains only trace amounts of natural 7-hydroxymitragynine. Millions of adults use natural kratom leaf products responsibly for its functional benefits. Conversely, concentrated synthetic 7-OH opioid products are potent by design, containing synthetic 7-OH at more than 100 times the level found in natural kratom leaf. The result is a novel opioid 13 times stronger than morphine -- this presents a high risk for addiction, respiratory depression and death.

The Global Kratom Coalition urges other states to follow Kentucky’s example -- protect public health by scheduling concentrated synthetic 7-OH, while protecting access to natural kratom leaf.

Media Contact

Patrick George

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SOURCE: Global Kratom Coalition (GKC)

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